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In the modern review, we described the identification as well as characterization of a brand new atypical opioid receptor with exclusive adverse regulatory Attributes to opioid peptides.1 Our final results showed that ACKR3/CXCR7, hitherto known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is additionally a broad-spectrum sca